Gonadorelina [INN-Spanish]
Brand names,
Gonadorelina [INN-Spanish]
Analogs
Gonadorelina [INN-Spanish]
Brand Names Mixture
Gonadorelina [INN-Spanish]
Chemical_Formula
(FeO.OH.2H2O)478 (Dx.COOH)9
Gonadorelina [INN-Spanish]
RX_link
http://www.rxlist.com/cgi/generic3/fedex.htm
Gonadorelina [INN-Spanish]
fda sheet
Gonadorelina [INN-Spanish]
msds (material safety sheet)
Gonadorelina [INN-Spanish]
Synthesis Reference
No information avaliable
Gonadorelina [INN-Spanish]
Molecular Weight
105000 g/mol (average)
Gonadorelina [INN-Spanish]
Melting Point
No information avaliable
Gonadorelina [INN-Spanish]
H2O Solubility
Soluble
Gonadorelina [INN-Spanish]
State
Solid
Gonadorelina [INN-Spanish]
LogP
No information avaliable
Gonadorelina [INN-Spanish]
Dosage Forms
Solution (for intramuscular injection)
Gonadorelina [INN-Spanish]
Indication
For treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD) - Chronic Kidney Disease patients receiving an erythropoietin.
Gonadorelina [INN-Spanish]
Pharmacology
Iron dextran is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. It is for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Iron is essential to the formation of hemoglobin and to the function and formation of other heme and nonheme compounds. Untreated depletion of iron stores leads to iron-deficient erythropoiesis and, in turn, to iron deficiency anemia.
Gonadorelina [INN-Spanish]
Absorption
The major portion of intramuscular injections of iron dextran is absorbed within 72 hours; most of the remaining iron is absorbed over the ensuing 3 to 4 weeks.
Gonadorelina [INN-Spanish]
side effects and Toxicity
LD50 = 500 mg/kg (mouse, IV). Dosages of iron dextran in excess of the requirements for restoration of hemoglobin and replenishment of iron stores may lead to hemosiderosis. Cases of severe, sometimes fatal, allergic reactions (loss of consciousness, collapse, difficulty breathing, hives, swelling, or convulsions) and severe low blood pressure (hypotension) have been reported with the use of iron dextran.
Gonadorelina [INN-Spanish]
Patient Information
http://www.drugs.com/cons/Inulin.html
Gonadorelina [INN-Spanish]
Organisms Affected
Humans and other mammals